Semax
Overview
A synthetic heptapeptide analog of the ACTH(4-7) fragment (Met-Glu-His-Phe-Pro-Gly-Pro) with nootropic and neuroprotective properties. Semax modulates BDNF and NGF expression, enhances monoaminergic neurotransmission, and provides neuroprotection through anti-oxidant and anti-inflammatory mechanisms. It crosses the blood-brain barrier via intranasal administration.
Key Research Findings
Approved in Russia and Ukraine for treatment of stroke, cognitive disorders, and optic nerve disease. Clinical studies demonstrated improved memory, attention, and cognitive performance. Research shows upregulation of BDNF and trkB expression in the hippocampus and cortex.
Intranasal
FDA Approved
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