Evidence-Based Research

Peptide Research Database

86Peptides Cataloged
51FDA Approved
11In Clinical Trials
24Research / Investigational

Showing 86 of 86 peptides

BPC-157

Recovery
Research Phase

A synthetic gastric pentadecapeptide derived from a protein found in human gastric juice. BPC-157 promotes angiogenesis and the expression of growth f...

Subcutaneous injection, Oral

TB-500 (Thymosin Beta-4)

Recovery
In Clinical Trials

Thymosin Beta-4 is a 43-amino acid actin-sequestering protein involved in cell migration, differentiation, and tissue repair. It promotes wound healin...

Subcutaneous injection

GHK-Cu

Recovery
Research Phase

A naturally occurring copper-binding tripeptide (glycyl-L-histidyl-L-lysine) found in human plasma, saliva, and urine. GHK-Cu activates tissue remodel...

Topical, Subcutaneous injection

DSIP (Delta Sleep-Inducing Peptide)

Recovery
Research Phase

A naturally occurring nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) originally isolated from cerebral venous blood of rabbits during induced sleep...

Subcutaneous injection, Intravenous, Intranasal

Pentosan Polysulfate (Elmiron)

Recovery
FDA Approved

A semi-synthetic sulfated polysaccharide derived from beechwood hemicellulose with structural similarities to glycosaminoglycans. Pentosan polysulfate...

Oral

Semaglutide (Ozempic/Wegovy)

Metabolic
FDA Approved

A glucagon-like peptide-1 receptor agonist (GLP-1 RA) with 94% amino acid homology to native GLP-1. Semaglutide enhances glucose-dependent insulin sec...

Subcutaneous injection (weekly), Oral (daily - Rybelsus)

Tirzepatide (Mounjaro/Zepbound)

Metabolic
FDA Approved

A first-in-class dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist. Tirzepatide activates both incretin pathways simu...

Subcutaneous injection (weekly)

Retatrutide

Metabolic
In Clinical Trials

An investigational triple hormone receptor agonist targeting GLP-1, GIP, and glucagon receptors simultaneously. The glucagon receptor component adds t...

Subcutaneous injection (weekly)

AOD-9604

Metabolic
Investigational

A modified 16-amino acid fragment (amino acids 176-191) of the C-terminus of human growth hormone with an added tyrosine at the N-terminus. AOD-9604 r...

Subcutaneous injection, Oral

Liraglutide (Saxenda/Victoza)

Metabolic
FDA Approved

A GLP-1 receptor agonist with 97% homology to native GLP-1, modified with a fatty acid side chain (C-16 palmitoyl) enabling albumin binding and a half...

Subcutaneous injection (daily)

Exenatide (Byetta/Bydureon)

Metabolic
FDA Approved

A synthetic version of exendin-4, a 39-amino acid peptide originally isolated from the saliva of the Gila monster lizard (Heloderma suspectum). Exenat...

Subcutaneous injection (twice daily or weekly extended-release)

Glucagon

Metabolic
FDA Approved

A 29-amino acid peptide hormone produced by alpha cells of the pancreatic islets of Langerhans. Glucagon acts primarily on hepatocytes via the glucago...

Subcutaneous injection, Intramuscular injection, Intranasal

Pramlintide (Symlin)

Metabolic
FDA Approved

A synthetic analog of amylin (islet amyloid polypeptide), a 37-amino acid peptide hormone co-secreted with insulin from pancreatic beta cells. Pramlin...

Subcutaneous injection (before meals)

Dulaglutide (Trulicity)

Metabolic
FDA Approved

A long-acting GLP-1 receptor agonist consisting of a GLP-1 analog covalently linked to a modified human IgG4 Fc fragment via a peptide linker. This fu...

Subcutaneous injection (weekly)

Lixisenatide (Adlyxin)

Metabolic
FDA Approved

A selective GLP-1 receptor agonist derived from exendin-4 with a modified C-terminal tail containing six lysine residues. Lixisenatide has a half-life...

Subcutaneous injection (daily)

Setmelanotide (Imcivree)

Metabolic
FDA Approved

A cyclic peptide melanocortin-4 receptor (MC4R) agonist designed to restore MC4R signaling in patients with obesity caused by genetic deficiencies in ...

Subcutaneous injection (daily)

CJC-1295

Hormone
In Clinical Trials

A synthetic analog of growth hormone-releasing hormone (GHRH) with a Drug Affinity Complex (DAC) that binds to albumin, extending its half-life from m...

Subcutaneous injection

Ipamorelin

Hormone
In Clinical Trials

A highly selective growth hormone secretagogue that acts on ghrelin/GHS receptors in the pituitary gland to stimulate GH release. Unlike other GH secr...

Subcutaneous injection

Sermorelin

Hormone
FDA Approved

A synthetic 29-amino acid analog of GHRH representing the shortest fully functional fragment of the native 44-amino acid hormone. Sermorelin stimulate...

Subcutaneous injection

Tesamorelin (Egrifta)

Hormone
FDA Approved

A synthetic GHRH analog consisting of the 44-amino acid sequence of human GHRH with a trans-3-hexenoic acid modification at the N-terminus to improve ...

Subcutaneous injection (daily)

PT-141 (Bremelanotide / Vyleesi)

Hormone
FDA Approved

A synthetic cyclic heptapeptide melanocortin receptor agonist that activates MC3R and MC4R in the central nervous system. Unlike PDE5 inhibitors that ...

Subcutaneous injection (as needed)

Kisspeptin

Hormone
In Clinical Trials

A neuropeptide encoded by the KISS1 gene that serves as the master upstream regulator of the hypothalamic-pituitary-gonadal (HPG) axis. Kisspeptin act...

Intravenous, Subcutaneous injection

Oxytocin

Hormone
FDA Approved

A nine-amino acid cyclic neuropeptide produced in the hypothalamus and released from the posterior pituitary. Oxytocin mediates uterine contractions d...

Intravenous, Intramuscular injection, Intranasal

GHRP-2

Hormone
Investigational

A synthetic hexapeptide growth hormone secretagogue that acts on the ghrelin receptor (GHS-R1a) in the hypothalamus and pituitary to stimulate growth ...

Subcutaneous injection, Intravenous

GHRP-6

Hormone
Investigational

A synthetic hexapeptide growth hormone secretagogue that stimulates the anterior pituitary via GHS-R1a receptor activation. GHRP-6 produces significan...

Subcutaneous injection, Intravenous

Hexarelin

Hormone
Investigational

A synthetic hexapeptide growth hormone secretagogue with the highest GH-releasing potency among GHRPs. Hexarelin binds both GHS-R1a and CD36 (scavenge...

Subcutaneous injection, Intravenous

MK-677 (Ibutamoren)

Hormone
In Clinical Trials

An orally bioavailable, non-peptide growth hormone secretagogue that mimics the action of ghrelin at the GHS-R1a receptor. MK-677 stimulates sustained...

Oral

Macimorelin (Macrilen)

Hormone
FDA Approved

An orally bioavailable growth hormone secretagogue approved as a diagnostic agent for adult growth hormone deficiency (AGHD). Macimorelin stimulates G...

Oral

Cosyntropin (Cortrosyn)

Hormone
FDA Approved

A synthetic peptide consisting of the first 24 amino acids of the 39-amino acid adrenocorticotropic hormone (ACTH). Cosyntropin retains full biologica...

Intravenous, Intramuscular injection

Gonadorelin (GnRH)

Hormone
FDA Approved

A synthetic decapeptide identical to endogenous gonadotropin-releasing hormone. Gonadorelin stimulates the release of luteinizing hormone (LH) and fol...

Intravenous, Subcutaneous injection

Leuprolide (Lupron)

Reproductive
FDA Approved

A synthetic nonapeptide GnRH agonist approximately 15-fold more potent than native GnRH. After an initial stimulatory phase (flare effect) lasting 1-2...

Subcutaneous injection, Intramuscular injection (depot)

Goserelin (Zoladex)

Reproductive
FDA Approved

A synthetic decapeptide GnRH agonist administered as a biodegradable subcutaneous implant that provides sustained drug release over 1 or 3 months. Lik...

Subcutaneous implant

Cetrorelix (Cetrotide)

Reproductive
FDA Approved

A synthetic decapeptide GnRH antagonist that competitively blocks pituitary GnRH receptors, producing immediate and dose-dependent suppression of LH a...

Subcutaneous injection

Ganirelix

Reproductive
FDA Approved

A synthetic decapeptide GnRH antagonist that competitively and reversibly blocks GnRH receptors on pituitary gonadotroph cells. Ganirelix rapidly supp...

Subcutaneous injection

Carbetocin

Reproductive
In Clinical Trials

A long-acting synthetic analog of oxytocin with a modified disulfide bridge that confers resistance to enzymatic degradation. Carbetocin has a half-li...

Intravenous, Intramuscular injection

Atosiban

Reproductive
Investigational

A competitive oxytocin/vasopressin V1a receptor antagonist used as a tocolytic agent to delay preterm labor. Atosiban blocks oxytocin-mediated myometr...

Intravenous

Semax

Cognitive
FDA Approved

A synthetic heptapeptide analog of the ACTH(4-7) fragment (Met-Glu-His-Phe-Pro-Gly-Pro) with nootropic and neuroprotective properties. Semax modulates...

Intranasal

Selank

Cognitive
Investigational

A synthetic analog of the endogenous tetrapeptide tuftsin (Thr-Lys-Pro-Arg) with an added Pro-Gly-Pro sequence for stability. Selank exhibits anxiolyt...

Intranasal

Cerebrolysin

Cognitive
Investigational

A porcine brain-derived peptide preparation consisting of low-molecular-weight neuropeptides and free amino acids that mimic the action of endogenous ...

Intravenous, Intramuscular injection

P21 (Peptide)

Cognitive
Research Phase

A small synthetic peptide derived from the active region of ciliary neurotrophic factor (CNTF) designed to promote neurogenesis and synaptic plasticit...

Subcutaneous injection, Intranasal

Epithalon (Epitalon)

Longevity
Research Phase

A synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on the natural epithalamin peptide produced by the pineal gland. Epithalon activates telomerase, the ...

Subcutaneous injection, Intravenous

MOTS-c

Longevity
Research Phase

A mitochondrial-derived peptide encoded by the 12S rRNA gene of mitochondrial DNA. MOTS-c is a 16-amino acid peptide that acts as an exercise mimetic ...

Subcutaneous injection

Humanin

Longevity
Research Phase

A 24-amino acid mitochondrial-derived peptide encoded within the 16S rRNA region of mitochondrial DNA. Humanin exerts cytoprotective and neuroprotecti...

Subcutaneous injection, Intravenous

NAD+ Precursors (NMN)

Longevity
In Clinical Trials

Nicotinamide mononucleotide (NMN) is a direct biosynthetic precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme essential for cellular me...

Oral, Intravenous, Sublingual

SS-31 (Elamipretide)

Longevity
In Clinical Trials

A mitochondria-targeted tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that selectively concentrates in the inner mitochondrial membrane by binding to c...

Subcutaneous injection, Intravenous

FOXO4-DRI

Longevity
Research Phase

A D-retro-inverso peptide designed to disrupt the interaction between FOXO4 and p53 in senescent cells. In senescent cells, FOXO4 sequesters p53 away ...

Subcutaneous injection, Intravenous

Thymalin

Immune
Investigational

A peptide bioregulator originally extracted from bovine thymus gland, consisting of a mixture of polypeptides that modulate immune function. Thymalin ...

Intramuscular injection

LL-37

Immune
Research Phase

The only human cathelicidin antimicrobial peptide, a 37-amino acid cationic peptide cleaved from the precursor protein hCAP18. LL-37 disrupts microbia...

Subcutaneous injection, Topical

VIP (Vasoactive Intestinal Peptide)

Immune
Investigational

A 28-amino acid neuropeptide widely distributed in the central and peripheral nervous systems and immune cells. VIP acts through VPAC1 and VPAC2 recep...

Intranasal, Intravenous, Subcutaneous injection

Thymosin Alpha 1 (Zadaxin)

Immune
Investigational

A 28-amino acid peptide originally isolated from thymic tissue (thymosin fraction 5) that serves as a potent immunomodulator. Thymosin alpha 1 enhance...

Subcutaneous injection

Thymopentin (TP-5)

Immune
Investigational

A synthetic pentapeptide (Arg-Lys-Asp-Val-Tyr) corresponding to residues 32-36 of thymopoietin, a thymic hormone involved in T-cell differentiation. T...

Subcutaneous injection, Intramuscular injection

Thymulin

Immune
Research Phase

A zinc-containing nonapeptide (facteur thymique serique) produced exclusively by thymic epithelial cells. Thymulin requires zinc for biological activi...

Subcutaneous injection, Intranasal

KPV

Immune
Research Phase

A C-terminal tripeptide fragment (Lys-Pro-Val) of alpha-melanocyte-stimulating hormone (alpha-MSH) that retains potent anti-inflammatory activity with...

Oral, Topical, Subcutaneous injection

Enfuvirtide (Fuzeon)

Antimicrobial
FDA Approved

A 36-amino acid synthetic peptide that inhibits HIV-1 entry into CD4+ T-cells by blocking the gp41-mediated membrane fusion step. Enfuvirtide binds to...

Subcutaneous injection (twice daily)

Melanotan II

Performance
Research Phase

A synthetic cyclic analog of alpha-melanocyte stimulating hormone (alpha-MSH) that non-selectively activates melanocortin receptors MC1R through MC5R....

Subcutaneous injection

Teriparatide (Forteo)

Bone
FDA Approved

A recombinant form of the first 34 amino acids of human parathyroid hormone (PTH 1-34). When administered intermittently via daily subcutaneous inject...

Subcutaneous injection (daily)

Abaloparatide (Tymlos)

Bone
FDA Approved

A synthetic 34-amino acid peptide analog of parathyroid hormone-related protein (PTHrP 1-34) that selectively activates the RG conformation of the PTH...

Subcutaneous injection (daily)

Calcitonin

Bone
FDA Approved

A 32-amino acid peptide hormone naturally produced by parafollicular C-cells of the thyroid gland. Calcitonin inhibits osteoclast-mediated bone resorp...

Intranasal, Subcutaneous injection, Intramuscular injection

Vosoritide (Voxzogo)

Bone
FDA Approved

A C-type natriuretic peptide (CNP) analog that acts as an agonist at the natriuretic peptide receptor B (NPR-B) on growth plate chondrocytes. Vosoriti...

Subcutaneous injection (daily)

Vasopressin (ADH)

Renal
FDA Approved

A nine-amino acid cyclic peptide hormone (arginine vasopressin) produced in the hypothalamus and released from the posterior pituitary. Vasopressin ac...

Intravenous, Intramuscular injection, Subcutaneous injection

Desmopressin (DDAVP)

Renal
FDA Approved

A synthetic analog of vasopressin with enhanced V2 receptor selectivity and minimal V1a vasopressor activity. Desmopressin has a deaminated cysteine a...

Intranasal, Oral, Subcutaneous injection, Intravenous

Terlipressin

Renal
FDA Approved

A synthetic vasopressin analog and prodrug that is cleaved by endopeptidases to release lysine-vasopressin. Terlipressin has greater V1a receptor sele...

Intravenous

Eptifibatide (Integrilin)

Cardiovascular
FDA Approved

A synthetic cyclic heptapeptide modeled after the KGD (Lys-Gly-Asp) disintegrin sequence found in the venom of the southeastern pygmy rattlesnake (Sis...

Intravenous

Nesiritide (Natrecor)

Cardiovascular
FDA Approved

A recombinant form of human B-type natriuretic peptide (BNP), a 32-amino acid peptide naturally produced by ventricular cardiomyocytes in response to ...

Intravenous

Angiotensin II (Giapreza)

Cardiovascular
FDA Approved

A synthetic form of the endogenous octapeptide angiotensin II, the primary effector of the renin-angiotensin system. Angiotensin II acts on AT1 recept...

Intravenous

Bivalirudin (Angiomax)

Hematology
FDA Approved

A synthetic 20-amino acid peptide that acts as a direct thrombin inhibitor by binding both the catalytic active site and anion-binding exosite 1 of th...

Intravenous

Romiplostim (Nplate)

Hematology
FDA Approved

A thrombopoietin (TPO) receptor agonist consisting of a peptide sequence that binds the TPO receptor (c-Mpl) fused to an IgG1 Fc domain (peptibody). R...

Subcutaneous injection (weekly)

Pegcetacoplan (Empaveli)

Hematology
FDA Approved

A pegylated cyclic peptide that inhibits complement component C3, the central node of all three complement activation pathways (classical, lectin, and...

Subcutaneous infusion

Carfilzomib (Kyprolis)

Oncology
FDA Approved

A tetrapeptide epoxyketone proteasome inhibitor that irreversibly binds the chymotrypsin-like (beta5) subunit of the 20S proteasome. By blocking prote...

Intravenous

Bortezomib (Velcade)

Oncology
FDA Approved

A modified dipeptidyl boronic acid that reversibly inhibits the chymotrypsin-like activity of the 26S proteasome. Bortezomib disrupts the ubiquitin-pr...

Subcutaneous injection, Intravenous

Lutetium-177 dotatate (Lutathera)

Oncology
FDA Approved

A radiolabeled somatostatin analog consisting of the peptide DOTA-Tyr3-octreotate chelated to the beta-emitting radioisotope lutetium-177. Lutathera b...

Intravenous

Leuprolide (Lupron) - Oncology

Oncology
FDA Approved

A GnRH agonist used in oncology for androgen deprivation therapy (ADT) in prostate cancer and hormone suppression in premenopausal breast cancer. Chro...

Intramuscular injection (depot), Subcutaneous injection

Octreotide (Sandostatin)

Gastrointestinal
FDA Approved

A synthetic octapeptide analog of somatostatin with a substantially longer half-life (90 minutes IV, 6 hours subcutaneous vs. 2 minutes for native som...

Subcutaneous injection, Intramuscular injection (LAR), Intravenous

Lanreotide (Somatuline Depot)

Gastrointestinal
FDA Approved

A synthetic octapeptide analog of somatostatin with high affinity for SSTR2 and moderate affinity for SSTR5 receptors. Lanreotide is formulated as a s...

Deep subcutaneous injection (monthly)

Pasireotide (Signifor)

Gastrointestinal
FDA Approved

A multireceptor-targeted somatostatin analog with high binding affinity for SSTR1, SSTR2, SSTR3, and SSTR5, particularly notable for its 40-fold great...

Subcutaneous injection (twice daily), Intramuscular injection (monthly LAR)

Plecanatide (Trulance)

Gastrointestinal
FDA Approved

A synthetic 16-amino acid peptide structurally related to uroguanylin, an endogenous intestinal peptide that regulates fluid and electrolyte homeostas...

Oral

Linaclotide (Linzess)

Gastrointestinal
FDA Approved

A synthetic 14-amino acid peptide structurally related to the heat-stable enterotoxin of Escherichia coli and the endogenous peptide guanylin. Linaclo...

Oral

Secretin

Gastrointestinal
FDA Approved

A 27-amino acid peptide hormone produced by S-cells of the duodenal and jejunal mucosa in response to acidic chyme entering the small intestine. Secre...

Intravenous

Larazotide

Gastrointestinal
In Clinical Trials

A synthetic octapeptide derived from Vibrio cholerae zonula occludens toxin that acts as a tight junction regulator. Larazotide acetate modulates inte...

Oral

Ziconotide (Prialt)

Pain
FDA Approved

A synthetic 25-amino acid peptide identical to omega-conotoxin MVIIA, a neurotoxin found in the venom of the marine cone snail Conus magus. Ziconotide...

Intrathecal infusion

Difelikefalin (Korsuva)

Pain
FDA Approved

A selective kappa-opioid receptor (KOR) agonist peptide that does not cross the blood-brain barrier, providing peripheral analgesia and anti-pruritic ...

Intravenous (post-dialysis)

ARA-290

Pain
In Clinical Trials

A synthetic 11-amino acid peptide derived from the structure of erythropoietin (EPO) that selectively activates the innate repair receptor (IRR), a he...

Subcutaneous injection, Intravenous

Afamelanotide (Scenesse)

Dermatology
FDA Approved

A synthetic 13-amino acid analog of alpha-melanocyte-stimulating hormone (alpha-MSH) with a substitution of norleucine at position 4 that confers enha...

Subcutaneous implant

Pentagastrin

Diagnostic
FDA Approved

A synthetic pentapeptide containing the C-terminal tetrapeptide sequence of gastrin (Trp-Met-Asp-Phe-NH2) linked to beta-alanine. Pentagastrin stimula...

Subcutaneous injection, Intramuscular injection

Icatibant (Firazyr)

Immune
FDA Approved

A synthetic decapeptide bradykinin B2 receptor antagonist containing five non-natural amino acids for enhanced stability and receptor selectivity. Ica...

Subcutaneous injection

Palmitoylethanolamide (PEA)

Pain
Research Phase

An endogenous fatty acid amide belonging to the N-acylethanolamine family, naturally produced by cells in response to tissue damage and inflammation. ...

Oral

Looking for a Provider Who Understands Peptide Science?

Our verified providers stay current with the latest peptide research and follow evidence-based protocols.

Research Sources & Disclaimer

Data in this database is compiled from peer-reviewed literature indexed on PubMed / MEDLINE, clinical trial registries at ClinicalTrials.gov, and drug monographs from the National Institutes of Health (NIH) and FDA drug approval databases. Regulatory status reflects U.S. FDA classification unless otherwise noted.

This database is for educational and informational purposes only and does not constitute medical advice. Many peptides listed are investigational and not approved for clinical use. Consult a qualified healthcare provider before considering any peptide therapy. Research status and findings are current as of early 2026 and subject to change as new data emerges.