GHK-Cu
Overview
A naturally occurring copper-binding tripeptide (glycyl-L-histidyl-L-lysine) found in human plasma, saliva, and urine. GHK-Cu activates tissue remodeling by stimulating collagen synthesis, glycosaminoglycan production, and angiogenesis while suppressing fibrinogen synthesis. It modulates the activity of matrix metalloproteinases and influences over 4,000 genes related to tissue repair.
Key Research Findings
Studies demonstrate promotion of collagen types I and III synthesis, accelerated wound healing, and increased hair follicle size. Gene expression analysis shows broad regenerative gene activation. Topical application improves skin elasticity, firmness, and reduces photodamage.
Topical, Subcutaneous injection
Research Phase
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