HormoneFDA Approved

Somatropin (Genotropin)

Subcutaneous injection

Overview

Somatropin is recombinant human growth hormone (rhGH) consisting of 191 amino acids identical in sequence to endogenous pituitary growth hormone. It binds to growth hormone receptors on target tissues to stimulate linear growth, protein synthesis, lipolysis, and carbohydrate metabolism.

Mechanism of Action

Genotropin is one of several branded formulations of somatropin approved for multiple indications including pediatric growth hormone deficiency, Turner syndrome, and adult growth hormone deficiency..

Research Summary & Key Findings

FDA approval was granted in 1995 for pediatric growth hormone deficiency and subsequently expanded to include additional indications based on pivotal trials demonstrating improved height velocity in children and body composition benefits in adults. Long-term safety data spanning decades support its efficacy and tolerability profile across diverse populations. Genotropin remains a widely used first-line treatment for approved growth disorders.

Clinical Status

FDA Approved

Somatropin (Genotropin) has received FDA approval and is available for clinical use under appropriate medical supervision. Consult a qualified healthcare provider for prescribing information.

Administration Routes

Subcutaneous injection

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Disclaimer: This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any peptide therapy. The Peptide Association does not endorse or recommend any specific treatment protocol.