Ipamorelin
Overview
A highly selective growth hormone secretagogue that acts on ghrelin/GHS receptors in the pituitary gland to stimulate GH release. Unlike other GH secretagogues, ipamorelin does not significantly affect ACTH, cortisol, or prolactin levels, making it one of the most specific GH-releasing peptides.
Mechanism of Action
It works synergistically with GHRH analogs like CJC-1295..
Research Summary & Key Findings
Clinical studies confirmed dose-dependent GH release without significant effects on cortisol or other pituitary hormones. Phase II trials in post-surgical ileus showed accelerated bowel recovery. Favorable safety profile with minimal appetite stimulation compared to GHRP-6.
Clinical Status
Ipamorelin is currently undergoing clinical trials. It is not yet FDA-approved and is available only through clinical research settings or investigational protocols.
Administration Routes
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CJC-1295
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