CognitiveFDA Approved

Semax

Intranasal

Overview

A synthetic heptapeptide analog of the ACTH(4-7) fragment (Met-Glu-His-Phe-Pro-Gly-Pro) with nootropic and neuroprotective properties. Semax modulates BDNF and NGF expression, enhances monoaminergic neurotransmission, and provides neuroprotection through anti-oxidant and anti-inflammatory mechanisms.

Mechanism of Action

It crosses the blood-brain barrier via intranasal administration..

Research Summary & Key Findings

Approved in Russia and Ukraine for treatment of stroke, cognitive disorders, and optic nerve disease. Clinical studies demonstrated improved memory, attention, and cognitive performance. Research shows upregulation of BDNF and trkB expression in the hippocampus and cortex.

Clinical Status

FDA Approved

Semax has received FDA approval and is available for clinical use under appropriate medical supervision. Consult a qualified healthcare provider for prescribing information.

Administration Routes

Intranasal

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Disclaimer: This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any peptide therapy. The Peptide Association does not endorse or recommend any specific treatment protocol.