TB-500 (Thymosin Beta-4)
Overview
Thymosin Beta-4 is a 43-amino acid actin-sequestering protein involved in cell migration, differentiation, and tissue repair. It promotes wound healing by upregulating cell-building proteins such as actin and laminin, facilitating cell migration to sites of injury.
Mechanism of Action
TB-500 also has anti-inflammatory properties mediated through NF-kB pathway modulation..
Research Summary & Key Findings
Accelerated dermal wound repair and corneal epithelial healing in clinical studies. Phase II trials showed improved cardiac function post-myocardial infarction (RegeneRx Biopharmaceuticals).
Clinical Status
TB-500 (Thymosin Beta-4) is currently undergoing clinical trials. It is not yet FDA-approved and is available only through clinical research settings or investigational protocols.
Administration Routes
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