ImmuneResearch Phase

Granulysin

Intravenous, Subcutaneous injection

Overview

Granulysin is a 15-kDa antimicrobial and cytolytic protein expressed by cytotoxic T lymphocytes and natural killer cells. It disrupts microbial and tumor cell membranes via lipid interactions and induces apoptosis.

Mechanism of Action

The therapeutic rationale includes treatment of intracellular infections and cancer immunotherapy..

Research Summary & Key Findings

Preclinical studies have shown granulysin-mediated killing of mycobacteria, including Mycobacterium tuberculosis, as well as antitumor activity in vitro and in animal models. No clinical trials or approved formulations are currently available, and development remains at the research stage.

Clinical Status

Research Phase

Granulysin is in the research phase with limited clinical data in humans. Current evidence is primarily derived from preclinical (animal or in vitro) studies.

Administration Routes

IntravenousSubcutaneous injection

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Disclaimer: This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any peptide therapy. The Peptide Association does not endorse or recommend any specific treatment protocol.