MetabolicFDA Approved

Beinaglutide

Subcutaneous injection

Overview

Beinaglutide is a recombinant glucagon-like peptide-1 (GLP-1) receptor agonist engineered with structural modifications to prolong plasma half-life and improve metabolic stability. The peptide activates GLP-1 receptors on pancreatic beta cells, stimulating glucose-dependent insulin secretion while suppressing glucagon release, delaying gastric emptying, and promoting satiety.

Mechanism of Action

Its mechanism targets multiple pathways involved in glycemic control, making it suitable for the treatment of type 2 diabetes mellitus..

Research Summary & Key Findings

Beinaglutide received regulatory approval in China in 2019 for the treatment of type 2 diabetes based on domestic phase 3 trial data demonstrating significant HbA1c reductions and favorable weight effects. Published clinical evidence outside China remains limited, and the compound has not pursued regulatory pathways in the United States or European Union as of 2024.

Clinical Status

FDA Approved

Beinaglutide has received FDA approval and is available for clinical use under appropriate medical supervision. Consult a qualified healthcare provider for prescribing information.

Administration Routes

Subcutaneous injection

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Disclaimer: This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any peptide therapy. The Peptide Association does not endorse or recommend any specific treatment protocol.