MetabolicFDA Approved

Albiglutide (Tanzeum)

Subcutaneous injection

Overview

Albiglutide is a GLP-1 receptor agonist consisting of a tandem repeat of modified human GLP-1 sequences fused to human albumin, creating a protein of approximately 73 kilodaltons with extended pharmacokinetic properties. The albumin fusion technology allows for once-weekly dosing by delaying renal clearance and protecting the peptide from enzymatic degradation.

Mechanism of Action

By activating GLP-1 receptors, albiglutide enhances glucose-dependent insulin secretion and suppresses inappropriate glucagon release in patients with type 2 diabetes..

Research Summary & Key Findings

Albiglutide received FDA approval in 2014 for type 2 diabetes, and the HARMONY Outcomes trial published in Lancet (2018) demonstrated cardiovascular safety with a reduction in major adverse cardiovascular events. Despite positive trial results, the manufacturer voluntarily withdrew the product from global markets in 2018 for commercial reasons unrelated to safety or efficacy concerns.

Clinical Status

FDA Approved

Albiglutide (Tanzeum) has received FDA approval and is available for clinical use under appropriate medical supervision. Consult a qualified healthcare provider for prescribing information.

Administration Routes

Subcutaneous injection

Related Peptides in Metabolic

Semaglutide (Ozempic/Wegovy)

FDA Approved

A glucagon-like peptide-1 receptor agonist (GLP-1 RA) with 94% amino acid homology to native GLP-1. Semaglutide enhances...

View details

Tirzepatide (Mounjaro/Zepbound)

FDA Approved

A first-in-class dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist. Tirzepatide activat...

View details

Retatrutide

In Clinical Trials

An investigational triple hormone receptor agonist targeting GLP-1, GIP, and glucagon receptors simultaneously. The gluc...

View details

AOD-9604

Investigational

A modified 16-amino acid fragment (amino acids 176-191) of the C-terminus of human growth hormone with an added tyrosine...

View details

Find a Provider

Find a verified provider who offers Albiglutide (Tanzeum) therapy in your area.

Browse Provider Map

Find a Pharmacy

Browse PCAB-accredited and FDA 503B-registered compounding pharmacies that supply Albiglutide (Tanzeum).

Pharmacy Directory

Join the Association

Access exclusive peptide protocols, provider resources, and community support.

List Your Practice

Disclaimer: This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any peptide therapy. The Peptide Association does not endorse or recommend any specific treatment protocol.