Melanotan II
Overview
A synthetic cyclic analog of alpha-melanocyte stimulating hormone (alpha-MSH) that non-selectively activates melanocortin receptors MC1R through MC5R. Melanotan II stimulates melanogenesis for skin tanning via MC1R, modulates sexual arousal through MC3R/MC4R in the hypothalamus, and reduces appetite through central MC4R activation. It is not FDA-approved and carries significant safety concerns.
Key Research Findings
Research demonstrated effective UV-independent melanogenesis and photoprotective effects. Also showed erectogenic effects in clinical studies, leading to development of PT-141. Safety concerns include nausea, facial flushing, potential for melanocyte dysregulation, and unregulated product quality. Not approved by any major regulatory agency.
Subcutaneous injection
Research Phase
Interested in Melanotan II?
Find a verified provider experienced with Melanotan II protocols in your area. All providers are credentialed and use compliant sourcing.
Find a Melanotan II Provider